Data/hora: 06/06/2024 11:33:46

Provedor de dados: | 55
País: | Brazil
Título: | Herpes simplex virus ophthalmic disease induced using two different methods of mice inoculation
Autores: | Pereira,Sílvia Regina Ferreira Gonçalves; Guimarães,Maria Angélica A. M.; V. Neto,Leonardo; Segenreich,Daniel; Varella,Rafael Brandão; Chagas,Vera Lucia Antunes; Câmara,Fernando Portela.
Data: | 2001-08-01
Ano: | 2001
Palavras-chave: | Herpes simplex virus; Ophthalmic disease; Non-traumatic and traumatic inoculation; Murine model.
Resumo: | Two different procedures for inoculation of HSV on corneas of BALB/c mice were evaluated. The first was by the use of HSV suspensions directly on the corneas and the other was after corneal scarification. Animals by this later method presented greater morbidity and mortality than those of first group, suggesting that inoculation of HSV without scarification of the cornea should be the method of choice for the study of HSV ophthalmic infection. This model showed also be an efficient experimental system to testing antiviral drugs.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702001000400004
Editor: | Brazilian Society of Infectious Diseases
Relação: | 10.1590/S1413-86702001000400004
Formato: | text/html
Fonte: | Brazilian Journal of Infectious Diseases  v.5 n.4 2001
Fonte: | info:eu-repo/semantics/openAccess