Data/hora: 01/06/2024 02:37:49

Provedor de dados: | 55
País: | Brazil
Título: | KPC-producing Enterobacter aerogenes infection
Autores: | Tuon,Felipe F.; Scharf,Camila; Rocha,Jaime L.; Cieslinsk,Juliette; Becker,Guilherme Nardi; Arend,Lavinia N.
Data: | 2015-06-01
Ano: | 2015
Palavras-chave: | KPC Enterobacter; Carbapenemase; Infection control.
Resumo: | Background: Enterobacteris a common nosocomial microorganism and its carbapenem's resistance has increased. The management of these cases is unclear.Objective: We evaluated 16 patients with KPC-producing Enterobacter aerogenesinfections, detailing the site of infection, therapy, clinical and epidemiological data.Methods: A retrospective and descriptive study. Clinical data were revised and KPC-2 detection was by molecular methods. Risk factors associated with mortality were compared using appropriate tests according to variable type with a significance level of 0.05.Results: The 30-day mortality rate was 37.5% with no association with inadequate treatment. Age (p= 0.004) and Charlson score of comorbidities (p= 0.048) were independent risk factors associated with death in the multivariate analysis. The odds ratio for age &gt;43 years was 3.00 (95% CI: 1.02-9.32) and for Charlson score &gt;3 was 2.00 (95% CI: 1.08-3.71). Five strains were pan-resistant based on automated susceptibility tests. All patients were treated with monotherapy.Conclusion: The clinician should be alert to carbapenem-resistant Enterobacteriaceaeinfection in older patients with comorbidities. The mortality is high and we believe that prompt and adequate therapy must be employed.
Tipo: | Info:eu-repo/semantics/other
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702015000300324
Editor: | Brazilian Society of Infectious Diseases
Relação: | 10.1016/j.bjid.2015.01.003
Formato: | text/html
Fonte: | Brazilian Journal of Infectious Diseases  v.19 n.3 2015
Fonte: | info:eu-repo/semantics/openAccess