Data/hora: 01/06/2024 10:28:58

Provedor de dados: 	55	
País: 	Brazil	
Título: 	Successful treatment of pulmonary Nocardia farcinica infection with linezolid: case report and literature review	
Autores: 	Shen,Tian; Wu,Lihua; Geng,Lei; Wei,Zeqing; Zheng,Shusen.	
Data: 	2011-10-01	
Ano: 	2011	
Palavras-chave: 	Nocardia; Linezolid; Drug therapy; Transplantation.	
Resumo: 	Nocardia infection is rare but potentially fatal. Therapy of Nocardia infection remains difficult. Linezolid, a novel oxazolidinone antibiotic, has proven to be effective, but clinical data are limited. Here we describe a case of a 45-year-old man with pulmonary N. farcinica infection following a liver transplantation. The initial therapy was trimethoprim-sulfamethoxazole, which showed no effect. According to susceptibility test, linezolid was administered with clearly improving the patient's condition. The treatment was stopped for anemia as drug related adverse event, and the therapy lasted for as long as 5 months. At the end of treatment clinical cure was confirmed and anemia reversed after discontinuation of linezolid. We also analyzed the clinical data of previously published reports by literature review, focusing on the efficacy and safety of linezolid treatment for Nocardia infection.	
Tipo: 	Info:eu-repo/semantics/report	
Idioma: 	Inglês	
Identificador: 	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702011000500014	
Editor: 	Brazilian Society of Infectious Diseases	
Relação: 	10.1590/S1413-86702011000500014	
Formato: 	text/html	
Fonte: 	Brazilian Journal of Infectious Diseases  v.15 n.5 2011	
Fonte: 	info:eu-repo/semantics/openAccess