Data/hora: 12/06/2024 14:07:30

Provedor de dados: 	55	
País: 	Brazil	
Título: 	Toxoplasmic encephalitis: role of Human Leucocyte Antigens/alleles associated with rapid progression to Acquired Immunodeficiency Syndrome	
Autores: 	Rodrigues,Maria de Lourdes; Deghaide,Neifi Hassam; Figueiredo,José Fernando; de Menezes,Marcelo Bezerra; Demarco,Ana Lúcia; Donadi,Eduardo; Fernandes,Ana Paula.	
Data: 	2016-04-01	
Ano: 	2016	
Palavras-chave: 	HLA; AIDS; Encephalitis; T. gondii.	
Resumo: 	Abstract  Background/aims The frequency of Human Leucocyte Antigens/alleles associated with rapid progression from Human Immunodeficiency Virus infection to Acquired Immunodeficiency Syndrome was evaluated in Brazilian patients with Acquired Immunodeficiency Syndrome with and without Toxoplasmic Encephalitis.  Methods 114 patients with Acquired Immunodeficiency Syndrome (41 with Toxoplasmic Encephalitis, 43 with anti-Toxoplasma gondii antibodies, without Toxoplasmic Eencephalitis, and 30 without anti-Toxoplasma gondii antibodies circulating and without Toxoplasmic Encephalitis) were studied.  Results Human Leucocyte Antigens/alleles associated with rapid progression to Acquired Immunodeficiency Syndrome, particularly HLA-B35, -DR3, and -DR1 allele group, were significantly less represented in patients with Toxoplasmic Encephalitis and Acquired Immunodeficiency Syndrome.  Conclusion The presence of these Human Leucocyte Antigens/Alleles that predispose to Acquired Immunodeficiency Syndrome progression was associated with resistance to Toxoplasmic Encephalitis among Human Immunodeficiency Virus-1 carriers.	
Tipo: 	Info:eu-repo/semantics/article	
Idioma: 	Inglês	
Identificador: 	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702016000200115	
Editor: 	Brazilian Society of Infectious Diseases	
Relação: 	10.1016/j.bjid.2015.10.010	
Formato: 	text/html	
Fonte: 	Brazilian Journal of Infectious Diseases  v.20 n.2 2016	
Fonte: 	info:eu-repo/semantics/openAccess