Data/hora: 13/06/2024 04:08:42

Provedor de dados: 	55	
País: 	Brazil	
Título: 	The influenza season 2016/17 in Bucharest, Romania – surveillance data and clinical characteristics of patients with influenza-like illness admitted to a tertiary infectious diseases hospital	
Autores: 	Drăgănescu,Anca; Săndulescu,Oana; Florea,Dragoş; Vlaicu,Ovidiu; Streinu-Cercel,Anca; Oţelea,Dan; Aramă,Victoria; Luminos,Monica Luminiţa; Streinu-Cercel,Adrian; Niţescu,Maria; Ivanciuc,Alina; Bacruban,Rodica; Piţigoi,Daniela.	
Data: 	2018-10-01	
Ano: 	2018	
Palavras-chave: 	A/H3; B/Victoria; ILI; Influenza; SARI; Subtype.	
Resumo: 	ABSTRACT  Background: Influenza continues to drive seasonal morbidity, particularly in settings with low vaccine coverage.  Objectives: To describe the influenza cases and viral circulation among hospitalized patients.  Methods: A prospective study based on active surveillance of inpatients with influenza-like illness from a tertiary hospital in Bucharest, Romania, in the season 2016/17.  Results: A total of 446 patients were tested, with a balanced gender distribution. Overall, 192 (43%) patients tested positive for influenza, with the highest positivity rate in the age groups 3–13 years and &gt;65 years. Peak activity occurred between weeks 1 and 16/2017, with biphasic distribution: A viruses were replaced by B viruses from week 9/2017; B viruses predominated (66.1%). Among the 133 (69.3%) subtyped samples, all influenza A were subtype H3 (n = 57) and all influenza B were B/Victoria (n = 76). Patients who tested positive for influenza presented fewer comorbidities (p = 0.012), except for the elderly, in whom influenza was more common in patients with comorbidities (p = 0.050). Disease evolution was generally favorable under antiviral treatment. The length of hospital stay was slightly longer in patients with influenza-like illness who tested patients negative for influenza (p = 0.031).  Conclusions: Distinctive co-circulation of A/H3 and B/Victoria in Bucharest, Romania in the 2016/17 influenza season was found. While the A/H3 subtype was predominant throughout Europe that season, B/Victoria appears to have circulated specifically in Romania and the Eastern European region, predominantly affecting preschoolers and school children.	
Tipo: 	Info:eu-repo/semantics/article	
Idioma: 	Inglês	
Identificador: 	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702018000500377	
Editor: 	Brazilian Society of Infectious Diseases	
Relação: 	10.1016/j.bjid.2018.10.275	
Formato: 	text/html	
Fonte: 	Brazilian Journal of Infectious Diseases  v.22 n.5 2018	
Fonte: 	info:eu-repo/semantics/openAccess