Data/hora: 07/06/2024 04:47:38

Provedor de dados: | 55
País: | Brazil
Título: | Microbiology of the middle meatus compared to sputum in young patients with cystic fibrosis from Bahia - Brazil
Autores: | Tunes,Alessandro; Reis,Joice Neves; Terse,Regina; Santana,Maria Angélica; Diniz,Ana Lúcia; Barros,Tânia Fraga; Leal,Ana Karina Souza; Paixão,Vilma; Grassi,Maria Fernanda Rios.
Data: | 2014-04-01
Ano: | 2014
Palavras-chave: | Cystic fibrosis; Middle meatus; Infection; Endoscopy.
Resumo: | Lower airway infection is a major cause of morbidity and mortality in patients with cystic fibrosis. It is currently unknown if the infection of the upper airway can cause exacerbation of lower respiratory tract infection. This study aimed to determine the microbiological profile of the anterior paranasal sinuses outflow tract (middle meatus) of cystic fibrosis outpatients. The microbiological profile was defined using endoscopically directed middle meatal cultures. Paired middle meatal and sputum specimens were collected from 56 outpatients for aerobic cultures. A semi-quantitative leukocyte count of the middle meatal samples was performed. The median age of patients was nine years (3-20 years). Staphylococcus aureus (37%), Staphylococcuscoagulase-negative (25%), Neisseriac (14%), Pseudomonas aeruginosa (11%), andStreptococcus pneumoniae (7%) were the most prevalent microorganisms in the middle meatal cultures. Using the middle meatal leukocyte count, 16 out of 54 patients (29.6%) presented sinus infection. The most frequently identified pathogens in patients with sinus infections wereStaphylococcus aureus (10 patients), Pseudomonas aeruginosa (4 patients), andStreptococcus pneumoniae (3 patients). Agreement of paired middle meatal and sputum cultures was significantly higher among patients with infection in middle meatal (69%). The most common middle meatal pathogens were the typical cystic fibrosis spectrum. This suggests the potential for participating in post-nasal lower airway seeding.
Tipo: | Info:eu-repo/semantics/other
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702014000200215
Editor: | Brazilian Society of Infectious Diseases
Relação: | 10.1016/j.bjid.2013.07.006
Formato: | text/html
Fonte: | Brazilian Journal of Infectious Diseases  v.18 n.2 2014
Fonte: | info:eu-repo/semantics/openAccess