Data/hora: 05/06/2024 12:43:33

Provedor de dados: 	55	
País: 	Brazil	
Título: 	Anatomopathological study in BALB/c mice brains experimentally infected with Toxoplasma gondii	
Autores: 	Silva,Marcos Gontijo da; Lino Junior,Ruy de Souza; Costa,Tatiane Luiza da; Soares,Joanna D´arc Herzog; Amaral,Waldemar Naves do; Avelino,Mariza Martins; Castro,Ana Maria de.	
Data: 	2008-02-01	
Ano: 	2008	
Palavras-chave: 	Toxoplasmosis; Experimental histopathology; Mice brains.	
Resumo: 	Toxoplasmosis is one of the most important diseases of the nervous central system, leading to severe symptoms and, many times, irreversible sequelae. This work demonstrated the main anatomopathological lesions caused by Toxoplasma gondii in brains from experimentally infected BALB/c mice. We analyzed 51 cases of mice that developed toxoplasmosis after experimental infection by intraperitoneal inoculation of blood, amniotic liquid and cerebrospinal fluid from fetuses, newly born children and pregnant women with clinical and laboratory signals of toxoplasmosis. In all experiments where we detected the parasite in mice we also detected pathological lesions in the animal brains with great polymorphism between experiments. Edema was the most found lesion in all cases. Besides, it was possible to demonstrate the inflammatory process in 82.4% of cases and necrosis in 64.7% of cases, in agreement with the literature that describes severe neurological damage in its hosts.	
Tipo: 	Info:eu-repo/semantics/article	
Idioma: 	Inglês	
Identificador: 	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702008000100012	
Editor: 	Brazilian Society of Infectious Diseases	
Relação: 	10.1590/S1413-86702008000100012	
Formato: 	text/html	
Fonte: 	Brazilian Journal of Infectious Diseases  v.12 n.1 2008	
Fonte: 	info:eu-repo/semantics/openAccess