Data/hora: 12/06/2024 06:31:55

Provedor de dados: | 56
País: | Brazil
Título: | Decision support system for the diagnosis of schizophrenia disorders
Autores: | Razzouk,D.; Mari,J.J.; Shirakawa,I.; Wainer,J.; Sigulem,D.
Data: | 2006-01-01
Ano: | 2006
Palavras-chave: | Clinical decision support systems; Artificial intelligence; Decision making; Expert systems; Schizophrenia; Medical informatics.
Resumo: | Clinical decision support systems are useful tools for assisting physicians to diagnose complex illnesses. Schizophrenia is a complex, heterogeneous and incapacitating mental disorder that should be detected as early as possible to avoid a most serious outcome. These artificial intelligence systems might be useful in the early detection of schizophrenia disorder. The objective of the present study was to describe the development of such a clinical decision support system for the diagnosis of schizophrenia spectrum disorders (SADDESQ). The development of this system is described in four stages: knowledge acquisition, knowledge organization, the development of a computer-assisted model, and the evaluation of the system's performance. The knowledge was extracted from an expert through open interviews. These interviews aimed to explore the expert's diagnostic decision-making process for the diagnosis of schizophrenia. A graph methodology was employed to identify the elements involved in the reasoning process. Knowledge was first organized and modeled by means of algorithms and then transferred to a computational model created by the covering approach. The performance assessment involved the comparison of the diagnoses of 38 clinical vignettes between an expert and the SADDESQ. The results showed a relatively low rate of misclassification (18-34%) and a good performance by SADDESQ in the diagnosis of schizophrenia, with an accuracy of 66-82%. The accuracy was higher when schizophreniform disorder was considered as the presence of schizophrenia disorder. Although these results are preliminary, the SADDESQ has exhibited a satisfactory performance, which needs to be further evaluated within a clinical setting.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2006000100014
Editor: | Associação Brasileira de Divulgação Científica
Relação: | 10.1590/S0100-879X2006000100014
Formato: | text/html
Fonte: | Brazilian Journal of Medical and Biological Research  v.39 n.1 2006
Fonte: | info:eu-repo/semantics/openAccess