Data/hora: 06/06/2024 00:55:34

Provedor de dados: 	56	
País: 	Brazil	
Título: 	Food and the circadian activity of the hypothalamic-pituitary-adrenal axis	
Autores: 	Leal,A.M.O.; Moreira,A.C.	
Data: 	1997-12-01	
Ano: 	1997	
Palavras-chave: 	Feeding; Glucocorticoids; CRH; ACTH; Circadian rhythm.	
Resumo: 	Temporal organization is an important feature of biological systems and its main function is to facilitate adaptation of the organism to the environment. The daily variation of biological variables arises from an internal time-keeping system. The major action of the environment is to synchronize the internal clock to a period of exactly 24 h. The light-dark cycle, food ingestion, barometric pressure, acoustic stimuli, scents and social cues have been mentioned as synchronizers or" zeitgebers". The circadian rhythmicity of plasma corticosteroids has been well characterized in man and in rats and evidence has been accumulated showing daily rhythmicity at every level of the hypothalamic-pituitary-adrenal (HPA) axis. Studies of restricted feeding in rats are of considerable importance because they reveal feeding as a major synchronizer of rhythms in HPA axis activity. The daily variation of the HPA axis stress response appears to be closely related to food intake as well as to basal activity. In humans, the association of feeding and HPA axis activity has been studied under physiological and pathological conditions such as anorexia nervosa, bulimia, malnutrition, obesity, diabetes mellitus and Cushing's syndrome. Complex neuroanatomical pathways and neurochemical circuitry are involved in feeding-associated HPA axis modulation. In the present review we focus on the interaction among HPA axis rhythmicity, food ingestion, and different nutritional and endocrine states	
Tipo: 	Info:eu-repo/semantics/article	
Idioma: 	Inglês	
Identificador: 	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1997001200003	
Editor: 	Associação Brasileira de Divulgação Científica	
Relação: 	10.1590/S0100-879X1997001200003	
Formato: 	text/html	
Fonte: 	Brazilian Journal of Medical and Biological Research  v.30 n.12 1997	
Fonte: 	info:eu-repo/semantics/openAccess