Data/hora: 05/06/2024 01:33:15

Provedor de dados: 	56	
País: 	Brazil	
Título: 	Inflammatory biomarkers responses after acute whole body vibration in fibromyalgia	
Autores: 	Ribeiro,V.G.C.; Mendonça,V.A.; Souza,A.L.C.; Fonseca,S.F.; Camargos,A.C.R.; Lage,V.K.S.; Neves,C.D.C.; Santos,J.M.; Teixeira,L.A.C.; Vieira,E.L.M.; Teixeira Junior,A.L.; Mezêncio,B.; Fernandes,J.S.C.; Leite,H.R.; Poortmans,J.R.; Lacerda,A.C.R.	
Data: 	2018-01-01	
Ano: 	2018	
Palavras-chave: 	Biomarkers; Fibromyalgia; Clinical trial; Inflammation; Acute exercise.	
Resumo: 	The aims of this study were 1) to characterize the intensity of the vibration stimulation in women diagnosed with fibromyalgia (FM) compared to a control group of healthy women (HW) matched by age and anthropometric parameters, and 2) to investigate the effect of a single session of whole body vibration (WBV) on inflammatory responses. Levels of adipokines, soluble tumor necrosis factor receptors (sTNFr1, sTNFr2), and brain-derived neurotrophic factor (BDNF) were determined by enzyme-linked immunosorbent assay. Oxygen consumption (VO2) was estimated by a portable gas analysis system, heart rate (HR) was measured using a HR monitor, and perceived exertion (RPE) was evaluated using the Borg scale of perceived exertion. Acutely mild WBV increased VO2 and HR similarly in both groups. There was an interaction (disease vs vibration) in RPE (P=0.0078), showing a higher RPE in FM compared to HW at rest, which further increased in FM after acute WBV, whereas it remained unchanged in HW. In addition, there was an interaction (disease vs vibration) in plasma levels of adiponectin (P=0.0001), sTNFR1 (P=0.000001), sTNFR2 (P=0.0052), leptin (P=0.0007), resistin (P=0.0166), and BDNF (P=0.0179). In conclusion, a single acute session of mild and short WBV can improve the inflammatory status in patients with FM, reaching values close to those of matched HW at their basal status. The neuroendocrine mechanism seems to be an exercise-induced modulation towards greater adaptation to stress response in these patients.	
Tipo: 	Info:eu-repo/semantics/article	
Idioma: 	Inglês	
Identificador: 	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2018000400615	
Editor: 	Associação Brasileira de Divulgação Científica	
Relação: 	10.1590/1414-431x20176775	
Formato: 	text/html	
Fonte: 	Brazilian Journal of Medical and Biological Research  v.51 n.4 2018	
Fonte: 	info:eu-repo/semantics/openAccess