Data/hora: 02/06/2024 16:54:06

Provedor de dados: | 56
País: | Brazil
Título: | The impact of short daily hemodialysis on anemia and the quality of life in Chinese patients
Autores: | Jiang,J.L.; Ren,W.; Song,J.; Sun,Q.L.; Xiao,X.Y.; Diao,X.Z.; Huang,Y.H.; Lan,L.; Wang,P.; Hu,Z.
Data: | 2013-07-01
Ano: | 2013
Palavras-chave: | Short daily hemodialysis; Anemia; Erythropoietin; Quality of life; End-stage renal disease.
Resumo: | Anemia is a frequent complication in hemodialysis patients. Compared to conventional hemodialysis (CHD), short daily hemodialysis (sDHD) has been reported to be effective in many countries except China. The aim of the present study was to determine whether sDHD could improve anemia and quality of life (QOL) for Chinese outpatients with end-stage renal disease. Twenty-seven patients (16 males/11 females) were converted from CHD to sDHD. All laboratory values were measured before conversion (baseline), at 3 months after conversion (sDHD1), and at 6 months after conversion (sDHD2). The patient's QOL was evaluated at baseline and 6 months after conversion using the Medical Outcomes Study 36-Item Short Form Health Survey (SF-36). Hemoglobin concentration increased significantly from 107.4±7.9 g/L at baseline to 114.4±6.8 g/L (P&lt;0.05) at sDHD1, and 118.3±8.4 g/L (P&lt;0.001) at sDHD2 (Student paired t-test). However, the dose requirement for erythropoietin decreased from 6847.8±1057.3 U/week at baseline to 5869.6±1094.6 U/week (P&lt;0.05) at sDHD2. Weekly stdKt/V increased significantly from 2.05±0.13 at baseline to 2.73±0.20 (P&lt;0.001) at sDHD1, and 2.84±0.26 (P&lt;0.001) at sDHD2. C-reactive protein decreased from baseline to sDHD1 and sDHD2, but without statistically significant differences. Physical and mental health survey scores increased in the 6 months following conversion to sDHD. sDHD may increase hemoglobin levels, decrease exogenous erythropoietin dose requirements, and improve QOL in Chinese hemodialysis patients compared to CHD. A possible mechanism for improvement of clinical outcomes may be optimized management of uremia associated with the higher efficiency of sDHD.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2013000700629
Editor: | Associação Brasileira de Divulgação Científica
Relação: | 10.1590/1414-431X20132832
Formato: | text/html
Fonte: | Brazilian Journal of Medical and Biological Research  v.46 n.7 2013
Fonte: | info:eu-repo/semantics/openAccess