Data/hora: 05/06/2024 12:27:41

Provedor de dados: | 56
País: | Brazil
Título: | Development of fetal nicotine and muscarinic receptors in utero
Autores: | Mao,C.; Lv,J.; Li,H.; Chen,Y.; Wu,J.; Xu,Z.
Data: | 2007-05-01
Ano: | 2007
Palavras-chave: | Acetylcholine; Muscarinic/nicotinic receptors; Fetus; Swallowing; Vascular homeostasis.
Resumo: | The role of acetylcholine in the central and peripheral nervous systems is well established in adults. Cholinergic modulation of vascular functions and body fluid balance has been extensively studied. In the embryo-fetus, cholinergic receptors are widespread in the peripheral and central systems, including smooth muscle and the epithelial lining of the cardiovascular, digestive, and urinary systems, as well as in the brain. Fetal nicotine and muscarinic receptors develop in a pattern (e.g., amount and distribution) related to gestational periods. Cholinergic mechanisms have been found to be relatively intact and functional in the control of vascular homeostasis during fetal life in utero at least during the last third of gestation. This review focuses on the development of fetal nicotine and muscarinic receptors, and provides information indicating that central cholinergic systems are well developed in the control of fetal blood pressure and body fluid balance before birth. Therefore, the development of cholinergic systems in utero plays an important role in fetal vascular regulation, gastrointestinal motility, and urinary control.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2007000500019
Editor: | Associação Brasileira de Divulgação Científica
Relação: | 10.1590/S0100-879X2006005000094
Formato: | text/html
Fonte: | Brazilian Journal of Medical and Biological Research  v.40 n.5 2007
Fonte: | info:eu-repo/semantics/openAccess