Data/hora: 15/06/2024 02:25:36

Provedor de dados: | 56
País: | Brazil
Título: | Effect of aging on carotid artery stiffness and baroreflex sensitivity during head-out water immersion in man
Autores: | Ueno,L.M.; Miyachi,M.; Matsui,T.; Takahashi,K.; Yamazaki,K.; Hayashi,K.; Onodera,S.; Moritani,T.
Data: | 2005-04-01
Ano: | 2005
Palavras-chave: | Aging; Baroreflex sensitivity; Carotid compliance; Water immersion; Hypertension; Vascular stiffness.
Resumo: | To examine the possible age-related blood pressure (BP) deregulation in response to central hypervolemia, we measured spontaneous baroreflex sensitivity (SBRS), carotid arterial compliance (CC), and R-R interval coefficient of variation (RRICV) during basal and thermoneutral resting head-out-of-water immersion (HOWI) in 7 young (YG = 24.0 ± 0.8 years) and 6 middle-aged/older (OL = 59.3 ± 1.3 years) healthy men. Compared with basal conditions (YG = 19.6 ± 4.0 vs OL = 6.1 ± 1.5 ms/mmHg, P &lt; 0.05), SBRS remained higher in YG than OL during rest HOWI (YG = 23.6 ± 6.6 vs OL = 9.3 ± 2.1 ms/mmHg, P &lt; 0.05). The RRICV was significantly different between groups (YG = 6.5 ± 1.4 vs OL = 2.8 ± 0.4%, P &lt; 0.05) under HOWI. The OL group had no increase in CC, but a significant increase in systolic BP (basal = 115.3 ± 4.4 vs water = 129.3 ± 5.3 mmHg, P &lt; 0.05) under HOWI. In contrast, the YG group had a significant increase in CC (basal = 0.16 ± 0.01 vs water = 0.17 ± 0.02 mm²/mmHg, P &lt; 0.05) with no changes in systolic BP. SBRS was positively related to CC (r = 0.58, P &lt; 0.05 for basal vs r = 0.62, P &lt; 0.05 for water). Our data suggest that age-related vagal dysfunction and reduced CC may be associated with SBRS differences between YG and OL groups, and with BP elevation during HOWI in healthy older men.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2005000400018
Editor: | Associação Brasileira de Divulgação Científica
Relação: | 10.1590/S0100-879X2005000400018
Formato: | text/html
Fonte: | Brazilian Journal of Medical and Biological Research  v.38 n.4 2005
Fonte: | info:eu-repo/semantics/openAccess