Data/hora: 01/06/2024 05:49:41

Provedor de dados: 	56	
País: 	Brazil	
Título: 	Anatomical connections of the periaqueductal gray: specific neural substrates for different kinds of fear	
Autores: 	Vianna,D.M.L.; Brandão,M.L.	
Data: 	2003-05-01	
Ano: 	2003	
Palavras-chave: 	Periaqueductal gray; Defense reaction; Fear; Escape; Freezing; Periaqueductal gray columns.	
Resumo: 	The periaqueductal gray (PAG) has been traditionally considered to be an exit relay for defensive responses. Functional mapping of its subdivisions has advanced our knowledge of this structure, but synthesis remains difficult mainly because results from lesion and stimulation studies have not correlated perfectly. After using a strategy that combined both techniques and a reevaluation of the available literature on PAG function and connections, we propose here that freezing could be mediated by different PAG subdivisions depending on the presence of immediate danger or exposure to related signaling cues. These subdivisions are separate functional entities with distinct descending and ascending connections that are likely to play a role in different defensive responses. The existence of ascending connections also suggests that the PAG is not simply a final common path for defensive responses. For example, the possibility that indirect ascending connections to the cingulate cortex could play a role in the expression of freezing evoked by activation of the neural substrate of fear in the dorsal PAG has been considered.	
Tipo: 	Info:eu-repo/semantics/article	
Idioma: 	Inglês	
Identificador: 	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2003000500002	
Editor: 	Associação Brasileira de Divulgação Científica	
Relação: 	10.1590/S0100-879X2003000500002	
Formato: 	text/html	
Fonte: 	Brazilian Journal of Medical and Biological Research  v.36 n.5 2003	
Fonte: 	info:eu-repo/semantics/openAccess