Data/hora: 02/06/2024 19:13:48

Provedor de dados: | 56
País: | Brazil
Título: | Dietary cellulose has no effect on the regeneration of hemoglobin in growing rats with iron deficiency anemia
Autores: | Catani,M.; Amâncio,O.M.S.; Fagundes-Neto,U.; Morais,M.B.
Data: | 2003-06-01
Ano: | 2003
Palavras-chave: | Iron deficiency; Dietary fiber; Cellulose; Iron absorption.
Resumo: | The objective of the present study was to determine the effect of cellulose on intestinal iron absorption in rats during recovery from iron deficiency anemia. Twenty-one-day-old male Wistar-EPM rats were fed an iron-free ration for two weeks to induce anemia. At 5 weeks of age, the rats were divided into two groups (both groups receiving 35 mg of elemental iron per kg diet): cellulose group (N = 12), receiving a diet containing 100 g of cellulose/kg and control (N = 12), receiving a diet containing no cellulose. The fresh weight of the feces collected over a 3-day period between the 15th and 18th day of dietary treatment was 10.7 ± 3.5 g in the group receiving cellulose and 1.9 ± 1.2 g in the control group (P&lt;0.001). Total food intake was higher in the cellulose group (343.4 ± 22.0 g) than in the control (322.1 ± 13.1 g, P = 0.009) during the 3 weeks of dietary treatment. No significant difference was observed in weight gain (cellulose group = 132.8 ± 19.2, control = 128.0 ± 16.3 g), hemoglobin increment (cellulose group = 8.0 ± 0.8, control = 8.0 ± 1.0 g/dl), hemoglobin level (cellulose group = 12.3 ± 1.2, control = 12.1 ± 1.3 g/dl) or in hepatic iron levels (cellulose group = 333.6 ± 112.4, control = 398.4 ± 168.0 µg/g dry tissue). We conclude that cellulose does not adversely affect the regeneration of hemoglobin, hepatic iron level or the growth of rats during recovery from iron deficiency anemia.
Tipo: | Info:eu-repo/semantics/other
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2003000600002
Editor: | Associação Brasileira de Divulgação Científica
Relação: | 10.1590/S0100-879X2003000600002
Formato: | text/html
Fonte: | Brazilian Journal of Medical and Biological Research  v.36 n.6 2003
Fonte: | info:eu-repo/semantics/openAccess