Data/hora: 09/06/2024 06:12:16

Provedor de dados: | 56
País: | Brazil
Título: | Heparan sulfates and heparins: similar compounds performing the same functions in vertebrates and invertebrates?
Autores: | Nader,H.B.; Chavante,S.F.; dos-Santos,E.A.; Oliveira,F.W.; de-Paiva,J.F.; Jerônimo,S.M.B.; Medeiros,G.F.; de-Abreu,L.R.D.; Leite,E.L.; de-Sousa-Filho,J.F.; Castro,R.A.B.; Toma,L.; Tersariol,I.L.S.; Porcionatto,M.A.; Dietrich,C.P.
Data: | 1999-05-01
Ano: | 1999
Palavras-chave: | Heparin - occurrence and function; Heparan sulfate - occurrence and function; Heparin - invertebrates; Heparan sulfate - invertebrates; Heparin and heparan sulfate - structure.
Resumo: | The distribution and structure of heparan sulfate and heparin are briefly reviewed. Heparan sulfate is a ubiquitous compound of animal cells whose structure has been maintained throughout evolution, showing an enormous variability regarding the relative amounts of its disaccharide units. Heparin, on the other hand, is present only in a few tissues and species of the animal kingdom and in the form of granules inside organelles in the cytoplasm of special cells. Thus, the distribution as well as the main structural features of the molecule, including its main disaccharide unit, have been maintained through evolution. These and other studies led to the proposal that heparan sulfate may be involved in the cell-cell recognition phenomena and control of cell growth, whereas heparin may be involved in defense mechanisms against bacteria and other foreign materials. All indications obtained thus far suggest that these molecules perform the same functions in vertebrates and invertebrates.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1999000500005
Editor: | Associação Brasileira de Divulgação Científica
Relação: | 10.1590/S0100-879X1999000500005
Formato: | text/html
Fonte: | Brazilian Journal of Medical and Biological Research  v.32 n.5 1999
Fonte: | info:eu-repo/semantics/openAccess