Data/hora: 10/06/2024 12:05:27

Provedor de dados: | 56
País: | Brazil
Título: | Role of Tamm-Horsfall protein in the binding and in vivo phagocytosis of type 1 fimbriated Escherichia coli by mouse peritoneal macrophages
Autores: | Bastos,A.C.S.C.; Santos,L.B.; Tamashiro,W.M.S.C.; Yamada,A.T.; Oliveira,U.M.; Yano,T.
Data: | 2001-07-01
Ano: | 2001
Palavras-chave: | Tamm-Horsfall protein; Type 1 fimbriated E. coli; Phagocytosis.
Resumo: | Tamm-Horsfall glycoprotein (THP) contains manno-oligosaccharides that are recognized by type 1 fimbriae (F1) of Escherichia coli. In the present study, we examined the in vivo phagocytic activity of mouse peritoneal macrophages after treatment of bacteria with THP. At low THP concentrations (12.5 µg/ml and 50 µg/ml) no significant difference was observed in the phagocytosis of E. coli F1+. However, at high THP concentrations (500 µg/ml and 1250 µg/ml) we obtained a reduction of bacterial phagocytosis by mouse peritoneal macrophages.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001000700011
Editor: | Associação Brasileira de Divulgação Científica
Relação: | 10.1590/S0100-879X2001000700011
Formato: | text/html
Fonte: | Brazilian Journal of Medical and Biological Research  v.34 n.7 2001
Fonte: | info:eu-repo/semantics/openAccess