Data/hora: 07/06/2024 10:28:10

Provedor de dados: 	56	
País: 	Brazil	
Título: 	Pharmacological effects and behavioral interventions on memory consolidation and reconsolidation	
Autores: 	Baratti,C.M.; Boccia,M.M.; Blake,M.G.	
Data: 	2009-02-01	
Ano: 	2009	
Palavras-chave: 	Memory; Consolidation; Reconsolidation; Extinction; Inhibitory avoidance.	
Resumo: 	In this article, we will review some behavioral, pharmacological and neurochemical studies from our laboratory on mice, which might contribute to our understanding of the complex processes of memory consolidation and reconsolidation. We discuss the post-training (memory consolidation) and post-reactivation (memory reconsolidation) effects of icv infusions of hemicholinium, a central inhibitor of acetylcholine synthesis, of intraperitoneal administration of L-NAME, a non-specific inhibitor of nitric oxide synthase, of intrahippocampal injections of an inhibitor of the transcription factor NF-κB, and the exposure of mice to a new learning situation on retention performance of an inhibitory avoidance response. All treatments impair long-term memory consolidation and retrieval-induced memory processes different from extinction, probably in accordance with the "reconsolidation hypothesis".	
Tipo: 	Info:eu-repo/semantics/article	
Idioma: 	Inglês	
Identificador: 	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2009000200001	
Editor: 	Associação Brasileira de Divulgação Científica	
Relação: 	10.1590/S0100-879X2009000200001	
Formato: 	text/html	
Fonte: 	Brazilian Journal of Medical and Biological Research  v.42 n.2 2009	
Fonte: 	info:eu-repo/semantics/openAccess