Data/hora: 10/06/2024 19:13:28

Provedor de dados: 	58	
País: 	Brazil	
Título: 	Occurrence of killer Candida glabrata clinical isolates	
Autores: 	O,Arroyo-Helguera; Alejandro,De Las Penas; Irene,Castaño.	
Data: 	2012-09-01	
Ano: 	2012	
Palavras-chave: 	Candida glabrata; Killer activity; Yeast; Saccharomyces.	
Resumo: 	In this work we characterized the occurrence of killer activity in 64 Candida glabrata clinical isolates under different conditions. We found that only 6.25 % of the clinical isolates tested were positive for killer activity against a Saccharomyces cerevisiae W303 sensitive strain. Sensitivity of killer activity to different values of pH and temperatures was analyzed. We found that the killer activity presented by all isolates was resistant to every pH and temperature tested, although optimal activity was found at a range of pH values from 4 to 7 and at 37ºC. We did not observe extrachromosomal genetic elements associated with killer activity in any of the positive C. glabrata isolates. The killer effect was due to a decrease in viability and DNA fragmentation in sensitive yeast.	
Tipo: 	Info:eu-repo/semantics/article	
Idioma: 	Inglês	
Identificador: 	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822012000300005	
Editor: 	Sociedade Brasileira de Microbiologia	
Relação: 	10.1590/S1517-83822012000300005	
Formato: 	text/html	
Fonte: 	Brazilian Journal of Microbiology  v.43 n.3 2012	
Fonte: 	info:eu-repo/semantics/openAccess