Data/hora: 01/06/2024 06:41:17

Provedor de dados: 	58	
País: 	Brazil	
Título: 	Comparative analysis of two component signal transduction systems of the Lactobacillus acidophilus group	
Autores: 	Cui,Yanhua; Qu,Xiaojun.	
Data: 	2011-03-01	
Ano: 	2011	
Palavras-chave: 	Lactobacillus acidophilus group; Two component system; Histidine protein kinase; Response regulator protein; Bioinformatics analysis.	
Resumo: 	The Lactobacillus acidophilus group is a phylogenetically distinct group of closely related lactobacilli. Members of this group are considered to have probiotic properties and occupy different environmental niches. Bacteria generally sense and respond to environmental changes through two component systems (TCSs) which consist of a histidine protein kinase (HPK) and its cognate response regulator (RR). With the use of in silico techniques, the five completely sequenced L. acidophilus group genomes were scanned in order to predict TCSs. Five to nine putative TCSs encoding genes were detected in individual genomes of the L. acidophilus group. The L. acidophilus group HPKs and RRs were classified into subfamilies using the Grebe and Stock classification method. Putative TCSs were analyzed with respect to conserved domains to predict biological functions. Putative biological functions were predicted for the L. acidophilus group HPKs and RRs by comparing them with those of other microorganisms. Some of TCSs were putatively involved in a wide variety of functions which are related with probiotic ability, including tolerance to acid and bile, production of antimicrobial peptides, resistibility to the glycopeptide antibiotic vancomycin, and oxidative condition.	
Tipo: 	Info:eu-repo/semantics/article	
Idioma: 	Inglês	
Identificador: 	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822011000100019	
Editor: 	Sociedade Brasileira de Microbiologia	
Relação: 	10.1590/S1517-83822011000100019	
Formato: 	text/html	
Fonte: 	Brazilian Journal of Microbiology  v.42 n.1 2011	
Fonte: 	info:eu-repo/semantics/openAccess