Data/hora: 01/06/2024 09:58:44

Provedor de dados: | 58
País: | Brazil
Título: | Antibacterial activity of α-terpineol may induce morphostructural alterations in Escherichia coli
Autores: | Li,Li; Shi,Chaofeng; Yin,Zhongqiong; Jia,Renyong; Peng,Lianci; Kang,Shuai; Li,Zhengwen.
Data: | 2014-12-01
Ano: | 2014
Palavras-chave: | Α-terpineol; Escherichia coli; Antibacterial activity; TEM.
Resumo: | The antibacterial effect of α-terpineol from Cinnamomum longepaniculatum (Gamble) N. Chao leaf essential oils were studied with special reference to the mechanism of inhibiting the standard strain of Escherichia coli (CMCC (B) 44102) growth at ultrastructural level. Minimal inhibitory concentration (MIC) and minimal bactericidal concentration (MBC) and time-kill curves of α-terpineol were determined; Escherichia coli was treated with α-terpineol and observed under a transmission electron microscope. The MIC and MBC values of α-terpineol were all 0.78 µL/mL, and time-kill curves showed the concentration-dependent. Under the transmission electron microscopy (TEM), Escherichia coli exposed to MIC levels of α-terpineol exhibited decreased cell size and irregular cell shape, cell wall and cell membrane were ruptured, nucleus cytoplasm was reduced and nuclear area gathered aside. Results suggest that α-terpineol has excellent antibacterial activity and could induce morphological changes of Escherichia coli.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822014000400035
Editor: | Sociedade Brasileira de Microbiologia
Relação: | 10.1590/S1517-83822014000400035
Formato: | text/html
Fonte: | Brazilian Journal of Microbiology  v.45 n.4 2014
Fonte: | info:eu-repo/semantics/openAccess