Data/hora: 05/06/2024 16:15:16

Provedor de dados: | 58
País: | Brazil
Título: | Interference of tuberculosis on the performance of ELISAs used in the diagnosis of paratuberculosis in cattle
Autores: | Lilenbaum,Walter; Ferreira,Rachel; Marassi,Carla Dray; Ristow,Paula; Oelemann,Walter Martins Roland; Fonseca,Leila de Souza.
Data: | 2007-09-01
Ano: | 2007
Palavras-chave: | Paratuberculosis; Tuberculosis; Mycobacterium bovis; Mycobacterium avium paratuberculosis.
Resumo: | Forty-four cows from five herds infected with tuberculosis (TB) and without paratuberculosis (PTB), and 21 cows from a herd without either infection were studied. The cattle presented concordant results in both the skin test and gamma-interferon assay for TB and two commercial ELISAs for PTB. Animals were divided according to TB test results into Group A with 28 TB-infected animals, Group B with 16 TB-negative animals from infected herds, and Group C with 21 TB-negative cows from a tuberculosis-free herd (which were used as controls). Twenty of 28 animals from Group A (71.4%), 6/16 from Group B (37.5%) and none from Group C were reactive to PTB ELISAs, suggesting that these commercial kits were unable to distinguish between PTB and TB. It is proposed that natural occurring TB strongly interferes in the diagnosis of PTB and that commercial ELISAs cannot be considered reliable tools in the diagnosis of paratuberculosis in tuberculosis-infected herds.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822007000300016
Editor: | Sociedade Brasileira de Microbiologia
Relação: | 10.1590/S1517-83822007000300016
Formato: | text/html
Fonte: | Brazilian Journal of Microbiology  v.38 n.3 2007
Fonte: | info:eu-repo/semantics/openAccess