Data/hora: 16/06/2024 05:25:56

Provedor de dados: | 58
País: | Brazil
Título: | Antifungal activity of Cymbopogon winterianus jowitt ex bor against Candida albicans
Autores: | Oliveira,Wylly Araújo de; Pereira,Fillipe de Oliveira; Luna,Giliara Carol Diniz Gomes de; Lima,Igara Oliveira; Wanderley,Paulo Alves; Lima,Rita Baltazar de; Lima,Edeltrudes de Oliveira.
Data: | 2011-06-01
Ano: | 2011
Palavras-chave: | Candida albicans; Antifungal; Cymbopogon winterianus.
Resumo: | Candida albicans is an opportunistic yeast and a member of the normal human flora that commonly causes infections in patients with any type of deficiency of the immune system. The essential oils have been tested for antimycotic activity and pose much potential as antifungal agents. This work investigated the activity of the essential oil of Cymbopogon winterianus against C. albicans by MIC, MFC and time-kill methods. The essential oil (EO) was obtained by hydrodistillation using a Clevenger-type apparatus. It was tested fifteen strains of C. albicans. The MIC was determined by the microdilution method and the MFC was determined when an aliquot of the broth microdilution was cultivated in SDA medium. The phytochemical analysis of EO showed presence of citronellal (23,59%), geraniol (18,81%) and citronellol (11,74%). The EO showed antifungal activity, and the concentrations 625 µg/mL and 1250 µg/mL inhibited the growth of all strains tested and it was fungicidal, respectively. The antimicrobial activity of various concentrations of EO was analyzed over time, it was found concentration-dependent antifungal activity, whose behavior was similar to amphotericin B and nystatin.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822011000200004
Editor: | Sociedade Brasileira de Microbiologia
Relação: | 10.1590/S1517-83822011000200004
Formato: | text/html
Fonte: | Brazilian Journal of Microbiology  v.42 n.2 2011
Fonte: | info:eu-repo/semantics/openAccess