Data/hora: 02/06/2024 13:36:47

Provedor de dados: | 58
País: | Brazil
Título: | Inhibitory activity of compounds isolated from Polymnia sonchifolia on aflatoxin production by Aspergillus flavus
Autores: | Pak,Adriana; Gonçalez,Edlayne; Felicio,Joana D'arc; Pinto,Marina Mori; Rossi,Maria Helena; Simoni,Isabela Cristina; Lopes,Márcia Nasser.
Data: | 2006-06-01
Ano: | 2006
Palavras-chave: | Polymnia sonchifolia; Flavonoids; Melampolides; Aflatoxin; Aspergillus flavus.
Resumo: | Polymnia sonchifolia, commonly known as ";yacon";, was originally cultivated at Andes moutains in South America. Recently, the specie attracted worldwide attention because of its wide range of uses, for example in the control of diabetes melitus, besides the antifungal and pesticidal compounds were found in the leaves. This study describes the identification of two flavonoids: 3', 5, 7 trihydroxy-3, 4'-dimethoxyflavone (compound 1) and 3', 4', 5- trihydroxy-7-methoxy flavanone (compound 2) and two sesquiterpenes lactones: enhydrin (compound 3) and a mixture of enhydrin and uvedalin (compound 4) isolated from Polymnia sonchifolia leaves and their effects on the aflatoxin production by Aspergillus flavus. The identification of the compounds were achieved by ¹H and 13C NMR. All compounds were tested in different concentration, to evaluate the growth of Aspergillus flavus culture and the production of aflatoxin. The compound 1, at the concentration 15 mug/mL, inhibited 25% of the aflatoxin B1 production (p&lt;0.01). The compound 4 inhibited 34% and 76% of the fungal growth and AFB1 production respectively. These results show that Polymnia sonchifolia can be used for the development of agents to control aflatoxin B1 production by Aspergillus flavus.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822006000200018
Editor: | Sociedade Brasileira de Microbiologia
Relação: | 10.1590/S1517-83822006000200018
Formato: | text/html
Fonte: | Brazilian Journal of Microbiology  v.37 n.2 2006
Fonte: | info:eu-repo/semantics/openAccess