Data/hora: 05/06/2024 04:22:52

Provedor de dados: | 58
País: | Brazil
Título: | Epidemiology of oral HPV in the oral mucosa in women without signs of oral disease from Yucatan, Mexico
Autores: | Gonzalez-Losa,María del Refugio; Barrera,Ernesto Soria; Herrera-Pech,Verónica; Conde-Ferráez,Laura; Puerto-Solís,Marylin; Ayora-Talavera,Guadalupe.
Data: | 2015-03-01
Ano: | 2015
Palavras-chave: | Papillomavirus; Oral mucosa; HPV13; Mexico.
Resumo: | High-risk human papillomaviruses (HR-HPV) are considered necessary for the development of cervical cancer. Furthermore, there is no doubt that some types of oral squamous cell carcinoma are associated with HR-HPV. The epidemiology of oral HPV infections in healthy subjects remains unclear due to a lack of knowledge. The objective of this study was to investigate the epidemiology of human papillomavirus infections of the oral mucosa without pathology. A cross-sectional study was performed; samples from 390 women seeking prenatal care, Pap smears, family planning or gynecological diseases were studied. Oral cells were collected by direct swab sampling. Information regarding sociodemographic status, sexual behavior, infectious diseases, contraceptive history and tobacco and alcohol consumption were obtained through direct interviews. HPV and genotypes were detected by type-specific polymerase chain reaction. Our results revealed that 14% of the women studied had an oral HPV infection. Women ≤ 20 years of age had the highest HPV prevalence (24.5%). In total, seven genotypes were identified, including the high-risk genotypes 16, 18, 58 and 59 and the low-risk genotypes 6, 81 and 13, the latter of which is a type exclusive to oral mucosa. Sexual behavior was not associated with the presence of genital HPV types in the oral mucosa. Genital HPV types were present in the oral mucosa of women without associated clinical manifestations; however, sexual behavior was not associated with infection, and therefore others routes of transmission should be explored.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822015000100301
Editor: | Sociedade Brasileira de Microbiologia
Relação: | 10.1590/S1517-838246120130976
Formato: | text/html
Fonte: | Brazilian Journal of Microbiology  v.46 n.1 2015
Fonte: | info:eu-repo/semantics/openAccess