Data/hora: 05/06/2024 17:26:40

Provedor de dados: 	58	
País: 	Brazil	
Título: 	Pathogenic factors and antimicrobial resistance of Staphylococcus epidermidis associated with nosocomial infections occurring in intensive care units	
Autores: 	Michelim,Lessandra; Lahude,Michele; Araújo,Patricia R.; Giovanaz,Dirce S. H.; Müller,Gabriela; Delamare,Ana P.L.; Costa,Sérgio Olavo Pinto da; Echeverrigaray,Sérgio.	
Data: 	2005-03-01	
Ano: 	2005	
Palavras-chave: 	Staphylococcus epidermidis; Pathogenicity factors; Antibiotic resistance; Hospital infection.	
Resumo: 	Nosocomial infections constitute an important problem in hospitals, intensive care units (ICU) having the highest incidence of this type of infection. Staphylococci, especially Staphylococcus epidermidis and Staphylococcus aureus, are among the most important microorganisms associated with nosocomial infections. S. epidermidis is a common skin resident, and can be introduced into the clinical environment by patients and hospital staff. The situation in hospitals is aggravated by the emergence of multiresistant strains. We evaluated 98 hospital S. epidermidis isolates collected at neonatal, pediatric and adult ICUs and 20 S. epidermidis control skin resident isolates from healthy volunteers, for resistance to ten antibiotics and chemotherapeutic agents, and other pathogenicity factors. A high frequency (76.5%) of multiresistance was detected in clinical isolates, whereas community isolates were resistant to penicillin and ampicillin only. The frequency of multiresistant strains was 67.7% in the neonatal ICU, 66.6% in the pediatric ICU and 60.8% in the adult ICU, the lower frequency of multiresistant isolates in the adult ICU indicates a higher incidence of community strains in this unit. There were significantly higher frequencies of hemolytic, proteolytic and biofilm-forming isolates in the clinical isolates than the community isolates, indicating a higher incidence of strains with pathogenic potential in the hospital environment. Except for slight correlation with hemolytic activity there was no correlation between antibiotic multiresistance and pathogenicity factors.	
Tipo: 	Info:eu-repo/semantics/article	
Idioma: 	Inglês	
Identificador: 	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822005000100004	
Editor: 	Sociedade Brasileira de Microbiologia	
Relação: 	10.1590/S1517-83822005000100004	
Formato: 	text/html	
Fonte: 	Brazilian Journal of Microbiology  v.36 n.1 2005	
Fonte: 	info:eu-repo/semantics/openAccess