Data/hora: 10/06/2024 18:19:05

Provedor de dados: | 60
País: | Brazil
Título: | Mushroom tyrosinase inhibitory activity and major fatty acid constituents of Amazonian native flora oils
Autores: | Teixeira,Raquel da Silva; Rocha,Paula Rafaela; Polonini,Hudson Caetano; Brandão,Marcos Antônio Fernandes; Chaves,Maria das Graças Afonso Miranda; Raposo,Nádia Rezende Barbosa.
Data: | 2012-09-01
Ano: | 2012
Palavras-chave: | Amazonian plants/evaluation; Amazonian plants/dermatological use; Skin lightening agents; Tyrosinase/inhibition; Tyrosinase/in vitro evaluation; Melanin; Hyperpigmentation/treatment.
Resumo: | In order to treat hyperpigmentation-related problems, there has been a global trend in developing cosmetics claiming to have skin-whitening properties, which act by inhibiting melanin biosynthesis. The objective of this work was to evaluate the in vitro mushroom tyrosinase inhibitory activity of five Amazonian native flora oils, and so to verify the possibility of their incorporation into cosmetic products. In addition, the fatty acid composition of the essential oils was determined by gas chromatography-flame ionisation detection in order to determine the main components of these oils. The tyrosinase inhibitory activity of the tested oils was found to be in the following order: açaí (IA50 = 66.08 µg mL-1) &gt; tucumã &gt; patauá &gt; pracaxi &gt; castanha do Brasil. This study suggests that açaí oil has great potential in the treatment of hyperpigmentation and other related disorders, due to its considerable tyrosinase inhibitory activity.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502012000300006
Editor: | Universidade de São Paulo, Faculdade de Ciências Farmacêuticas
Relação: | 10.1590/S1984-82502012000300006
Formato: | text/html
Fonte: | Brazilian Journal of Pharmaceutical Sciences  v.48 n.3 2012
Fonte: | info:eu-repo/semantics/openAccess