Data/hora: 05/06/2024 18:34:00

Provedor de dados: | 60
País: | Brazil
Título: | Development and validation of UV spectrophotometric method for orbifloxacin assay and dissolution studies
Autores: | Cazedey,Edith Cristina Laignier; Salgado,Hérida Regina Nunes.
Data: | 2014-09-01
Ano: | 2014
Palavras-chave: | Medicines/quality control; Medicines/dissolution; Orbifloxacin/determination; UV spectrophotometry/quantitative analysis/validation.
Resumo: | New, simple and cost effective UV-spectrophotometric method was developed for the estimation of orbifloxacin in pharmaceutical formulation. Orbifloxacin was estimated at 290 nm in 0.5 M hydrochloric acid. Linearity range was found to be 1.0-6.0 μg mL-1. The method was tested and validated for various parameters according to main guidelines. The proposed method was successfully applied for the determination of orbifloxacin in tablets. The results demonstrated that the procedure is accurate, precise and reproducible, while being simple, economical and less time consuming. It can be suitably applied for the estimation of orbifloxacin in routine quality control and dissolution studies.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502014000300457
Editor: | Universidade de São Paulo, Faculdade de Ciências Farmacêuticas
Relação: | 10.1590/S1984-82502014000300003
Formato: | text/html
Fonte: | Brazilian Journal of Pharmaceutical Sciences  v.50 n.3 2014
Fonte: | info:eu-repo/semantics/openAccess