Data/hora: 12/06/2024 17:06:51

Provedor de dados: | 65
País: | Brazil
Título: | Mammary fibroadenomatoid hyperplasia in a heifer
Autores: | Silva,Lorena Ferreira; Silva,Luiz Antonio Franco da; Rabelo,Rogério Elias; Silva,Wanessa Patrícia Rodrigues da; Cassali,Geovanni Dantas; Gonçalves,Aline De Biasi Bassani; Sant’Ana,Fabiano José Ferreira de.
Data: | 2017-01-01
Ano: | 2017
Palavras-chave: | Mammary hyperplasia; Estrogen; Progesterone; Diseases of cattle.
Resumo: | ABSTRACT: This manuscript described the anatomopathological and immunohistochemical findings in a rare case of mammary fibroadenomatoid hyperplasia in a 12-month-old Holstein heifer. A yellow, multilobulated, firm 20cm x 9cm x 6.5cm mass affecting the right quarters of the udder was observed. Total mastectomy was performed. Microscopic evaluation revealed severe hyperplasia of the mammary epithelium and numerous well-differentiated and mildly pleomorphic acini. Additionally, moderate proliferation of the fibrous connective tissue and the myoepithelial cells near the proliferating acini was evident. About 50% of the proliferating epithelial cells showed positive nuclear labeling for estrogen and progesterone receptors, and approximately one-third were positive for Ki-67. In addition, the myoepithelial cells exhibited diffuse nuclear immunoreactivity for p63. Based on the clinical, morphologic, and immunohistochemical findings, a diagnosis of mammary fibroadenomatoid hyperplasia with probable influence of ovarian steroids was made.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782017000600552
Editor: | Universidade Federal de Santa Maria
Relação: | 10.1590/0103-8478cr20160943
Formato: | text/html
Fonte: | Ciência Rural  v.47 n.6 2017
Fonte: | info:eu-repo/semantics/openAccess