Data/hora: 09/06/2024 11:53:27

Provedor de dados: | 65
País: | Brazil
Título: | Necrotic enterocolitis in pigs naturally infected by porcine circovirus type 2
Autores: | Zlotowski,Priscila; Corrêa,André Mendes Ribeiro; Barcellos,David Emílio Santos Neves de; Cardoso,Marisa Ribeiro de Itapema; Vasconcelos,Anílton Cesar; Castro,Luiza Amaral de; Driemeier,David.
Data: | 2009-09-01
Ano: | 2009
Palavras-chave: | Necrotic enterocolitis; PCV2 infection; Swine.
Resumo: | Samples of intestine with necrotic enteritis from 63 pigs naturally infected with porcine circovirus type 2 (PCV2) were studied. Colon was the main target of PCV2 associated necrotic enteritis in 60 cases. Immunohistological investigations were carried out to detect the presence of PCV2 in necrotic lesions and to identify the type of cells infected by the virus. Crypt epithelial cells had positive labelling for PCV2 in 17 cases. Depletion of goblet cells occurred in 10 cases. In 24 necrotic enteritis cases, co-infection of PCV2 and Salmonella was identified. An increased rate of apoptosis in the crypt epithelial cells of the large intestine from PCV2 of naturally infected pigs was observed. Immunohistochemical findings confirmed the presence of PCV2 within cells from necrotic intestinal tissue, suggesting that PCV2 may play a role in the development of those lesions. Diagnosis of necrotic enteritis associated with PCV2 should be based on the detection of PCV2 antigen or DNA in the necrotizing lesions. However, bacteriological examination should be performed to rule out the presence of bacterial agents, since co-infections are likely to occur in PCV2 affected pigs.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782009000600025
Editor: | Universidade Federal de Santa Maria
Relação: | 10.1590/S0103-84782009005000115
Formato: | text/html
Fonte: | Ciência Rural  v.39 n.6 2009
Fonte: | info:eu-repo/semantics/openAccess