Data/hora: 01/06/2024 08:00:59

Provedor de dados: | 65
País: | Brazil
Título: | Peripheral neuropathy in a copper-deficient goat
Autores: | Almeida,Valdir Morais de; Chaves,Hisadora Advincula da Silva; Silva Filho,Givaldo Bom da; Ribeiro,Danielle Pimentel; Braga,Thaiza Campelo; Mendonça,Fábio de Souza.
Data: | 2017-01-01
Ano: | 2017
Palavras-chave: | Mineral deficiency; Paralysis; Monoplegia; Muscular atrophy; Ruminants.
Resumo: | ABSTRACT: This report aimed to describe a case of peripheral neuropathy in a copper-deficient goat, and highlights the clinical, and pathological features of the disease. The goat had low body score, hyporexia, alopecia, achromotrichia, left hindlimb protraction, paralysis with dragging of digit and difficulty to stand up and microcytic normochromic anemia. Copper concentration in serum was markedly lower (2.0µmol L-1) whereas the iron serum content was significantly increased (51.0µmol L-1). The main gross alteration was the reduction of the quadriceps vastus laterallis muscle volume. Histologically, there was atrophy of the quadriceps vastus laterallis muscle and presence of satellite cells, infiltration of lymphocytes, macrophages and replacement of the fibers by connective tissue. In the femoral nerve, there was axonal degeneration with myelin sheath expansion and presence of vacuoles, usually in chains and containing axonal debris or macrophages. Clinical, laboratorial and pathologic findings are consistent with peripheral neuropathy due to a severy copper deficiency.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782017001000552
Editor: | Universidade Federal de Santa Maria
Relação: | 10.1590/0103-8478cr20170248
Formato: | text/html
Fonte: | Ciência Rural  v.47 n.10 2017
Fonte: | info:eu-repo/semantics/openAccess