Data/hora: 06/06/2024 01:14:00

Provedor de dados: | 65
País: | Brazil
Título: | Susceptibility profile of Brazilian Rhodococcus equi isolates against azithromycin, clarithromycin and erythromycin
Autores: | Gressler,Letícia Trevisan; Silveira,Bibiana Petri da; Schwab,Marcelo Luís; Vargas,Agueda Castagna de; Pötter,Luciana; Botton,Sônia de Avila.
Data: | 2015-04-01
Ano: | 2015
Palavras-chave: | Macrolide; Minimum inhibitory concentration; Antimicrobial susceptibility; Rhodococcosis.
Resumo: | Rhodococcus equi infection treatment is usually a macrolide (azithromycin - AZM, clarithromycin - CLR and erythromycin - ERY) and rifampicin combination. However, resistance cases have been reported, especially for ERY. In view of the need of a study about Brazilian isolates susceptibility profile, this study aimed to characterize the minimum inhibitory concentration (MIC) of the macrolides - AZM, CLR and ERY - against 44 R. equi isolates. It was found all isolates CLR and AZM sensitive; however, for ERY, 27% (12/44) were classified as intermediate sensitivity. R. equi Brazilian isolates used here showed a large susceptibility profile, except against ERY, for which it was observed some resistance evidence. In order to avoid failures in the equine rhodococcosis therapy it was highlighted the importance of microbiological culture and antimicrobial susceptibility testing in vitro before beginning treatment
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782015000400680
Editor: | Universidade Federal de Santa Maria
Relação: | 10.1590/0103-8478cr20140746
Formato: | text/html
Fonte: | Ciência Rural  v.45 n.4 2015
Fonte: | info:eu-repo/semantics/openAccess