Data/hora: 11/06/2024 06:36:03

Provedor de dados: | 65
País: | Brazil
Título: | Cyclooxygenase-2 expression in epithelial neoplasms and its relevance as a targeted therapy in dogs
Autores: | Cunha,Rúbia Monteiro de Castro; Horta,Rodrigo dos Santos; Lavalle,Gleidice Eunice; Araújo,Roberto Baracat.
Data: | 2016-06-01
Ano: | 2016
Palavras-chave: | Cancer; Carcinoma; Immunohistochemistry; Antineoplastic drugs.
Resumo: | ABSTRACT: Targeted therapy of neoplasms is an emergent approach in human and veterinary medicine. Cyclooxygenase (COX) is a class of catalytic enzymes related to the formation of inflammatory mediators. COX-2 is expressed constitutively in a few body tissues, but it may be induced in specific pathophysiologic conditions, such as cancer. COX-2 expression in neoplams may be considered a potential predictive factor, due to the possible association of selective COX-2 inhibitors in adjuvant treatments. This scientific communication has the objective to report COX-2 expression in seven neoplasms of dogs and the usage of adjuvant treatment with COX-2 selective inhibitors as an effective and feasible option in cancer treatment.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782016000601050
Editor: | Universidade Federal de Santa Maria
Relação: | 10.1590/0103-8478cr20150794
Formato: | text/html
Fonte: | Ciência Rural  v.46 n.6 2016
Fonte: | info:eu-repo/semantics/openAccess