Data/hora: 17/06/2024 18:50:12

Provedor de dados: 	65	
País: 	Brazil	
Título: 	Cyclooxygenase-2 expression in epithelial neoplasms and its relevance as a targeted therapy in dogs	
Autores: 	Cunha,Rúbia Monteiro de Castro; Horta,Rodrigo dos Santos; Lavalle,Gleidice Eunice; Araújo,Roberto Baracat.	
Data: 	2016-06-01	
Ano: 	2016	
Palavras-chave: 	Cancer; Carcinoma; Immunohistochemistry; Antineoplastic drugs.	
Resumo: 	ABSTRACT: Targeted therapy of neoplasms is an emergent approach in human and veterinary medicine. Cyclooxygenase (COX) is a class of catalytic enzymes related to the formation of inflammatory mediators. COX-2 is expressed constitutively in a few body tissues, but it may be induced in specific pathophysiologic conditions, such as cancer. COX-2 expression in neoplams may be considered a potential predictive factor, due to the possible association of selective COX-2 inhibitors in adjuvant treatments. This scientific communication has the objective to report COX-2 expression in seven neoplasms of dogs and the usage of adjuvant treatment with COX-2 selective inhibitors as an effective and feasible option in cancer treatment.	
Tipo: 	Info:eu-repo/semantics/article	
Idioma: 	Inglês	
Identificador: 	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782016000601050	
Editor: 	Universidade Federal de Santa Maria	
Relação: 	10.1590/0103-8478cr20150794	
Formato: 	text/html	
Fonte: 	Ciência Rural  v.46 n.6 2016	
Fonte: 	info:eu-repo/semantics/openAccess