Data/hora: 16/06/2024 03:14:53

Provedor de dados: 	74	
País: 	Brazil	
Título: 	Lack of functional KL-VS polymorphism of the KLOTHO gene in the Korean population	
Autores: 	Kim,Hee-Kwon; Jeong,Byung-Hoon.	
Data: 	2016-09-01	
Ano: 	2016	
Palavras-chave: 	Aging; KLOTHO gene; KL-VS polymorphism; Population genetics.	
Resumo: 	Abstract The functional variant of the Klotho "KL-VS" stretch, which includes six polymorphisms in linkage disequilibrium, is reportedly associated with healthy aging and longevity in European and American populations. Among Asian populations, this variant has been observed in the Indian population but not in the Iranian population. An association between KL-VS polymorphism and aging has not been reported in Koreans. To investigate whether the KL-VS polymorphism could be associated with healthy aging and longevity in a Korean population, we analyzed genotype and allele frequencies of the KL-VS variant in a large Korean population sample. The KL-VS variant was not found in 874 Korean individuals. Thus, it is not possible to test its association to aging in the East Asian populations.	
Tipo: 	Info:eu-repo/semantics/other	
Idioma: 	Inglês	
Identificador: 	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572016000300370	
Editor: 	Sociedade Brasileira de Genética	
Relação: 	10.1590/1678-4685-GMB-2015-0160	
Formato: 	text/html	
Fonte: 	Genetics and Molecular Biology  v.39 n.3 2016	
Fonte: 	info:eu-repo/semantics/openAccess