Data/hora: 09/06/2024 14:53:41

Provedor de dados: 	74	
País: 	Brazil	
Título: 	Recurrence risks for isolated cases of nonsyndromic deafness	
Autores: 	Braga,Maria Cristina C.; Otto,Paulo A.	
Data: 	2004-01-01	
Ano: 	2004	
Palavras-chave: 	Nonsyndromic deafness; Recurrence risks; Genetic counseling.	
Resumo: 	We present, in this paper, general formulae developed so as to permit the calculation of the recurrence risks for isolated cases of nonsyndromic deafness in the offspring of nonconsanguineous and consanguineous couples. We included, in all analyzed situations, the following factors: (a) a generic degree of parental consanguinity; (b) a variable proportion of environmental (non-genetic) cases of the defect, so that the formulae can be easily applied to populations with any epidemiological profile; (c) a variable number of normal sibs of the propositus. Besides presenting the logic and the detailed derivation of all original formulae, we present tables for immediate use, with the numerical values of the recurrence risks as a function of the variables mentioned above.	
Tipo: 	Info:eu-repo/semantics/article	
Idioma: 	Inglês	
Identificador: 	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572004000200004	
Editor: 	Sociedade Brasileira de Genética	
Relação: 	10.1590/S1415-47572004000200004	
Formato: 	text/html	
Fonte: 	Genetics and Molecular Biology  v.27 n.2 2004	
Fonte: 	info:eu-repo/semantics/openAccess