Data/hora: 01/06/2024 01:19:59

Provedor de dados: 	74	
País: 	Brazil	
Título: 	Estimating the effects of population size and type on the accuracy of genetic maps	
Autores: 	Ferreira,Adésio; Silva,Marcia Flores da; Silva,Luciano da Costa e; Cruz,Cosme Damião.	
Data: 	2006-01-01	
Ano: 	2006	
Palavras-chave: 	Experimental populations; Mapping; Simulation; Markers.	
Resumo: 	Based on simulation studies, it was shown that the type and size of experimental populations can exert an influence on the accuracy of genetic maps. A hypothetical genome map (one chromosome with nine equidistant molecular markers) was generated for the following population types: F2 with dominant and co-dominant markers, backcrossing, recombinant inbred lines (RIL) and double-haploid. The population sizes were 50, 100, 150, 200, 500 and 1000 individuals and 100 simulations were made for each population. The inaccuracies of the populations with the lowest number of individuals were shown by inversions in the order of the markers and the establishment of more than one linkage group in up to 38% of the simulations, depending on the population type. Stress and variance values of the distances between adjacent markers were significantly reduced with the increased size of the population. More accurate maps were obtained for the co-dominant F2 and RIL whereas the maps for the dominant F2 population were less accurate. The higher the number of individuals, the more precise was the map. In all populations, a total of 200 individuals were considered as being sufficient for the construction of reasonably accurate genetic maps. Although this paper deals with plant populations this approach is equally applicable to other organisms.	
Tipo: 	Info:eu-repo/semantics/article	
Idioma: 	Inglês	
Identificador: 	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572006000100033	
Editor: 	Sociedade Brasileira de Genética	
Relação: 	10.1590/S1415-47572006000100033	
Formato: 	text/html	
Fonte: 	Genetics and Molecular Biology  v.29 n.1 2006	
Fonte: 	info:eu-repo/semantics/openAccess