Data/hora: 09/06/2024 08:24:35

Provedor de dados: 	74	
País: 	Brazil	
Título: 	PENCALC: a program for penetrance estimation in autosomal dominant diseases	
Autores: 	Horimoto,Andréa R.V. Russo; Onodera,Márcio T.; Otto,Paulo A.	
Data: 	2010-01-01	
Ano: 	2010	
Palavras-chave: 	Penetrance (rate; Value) computer program maximum likelihood estimation.	
Resumo: 	We present a computer program developed for estimating penetrance rates in autosomal dominant diseases by means of family kinship and phenotype information contained within the pedigrees. The program also determines the exact 95% credibility interval for the penetrance estimate. Both executable (PenCalc for Windows) and web versions (PenCalcWeb) of the software are available. The web version enables further calculations, such as heterozygosity probabilities and assessment of offspring risks for all individuals in the pedigrees. Both programs can be accessed and down-loaded freely at the home-page address http://www.ib.usp.br/~otto/software.htm.	
Tipo: 	Info:eu-repo/semantics/article	
Idioma: 	Inglês	
Identificador: 	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572010000300012	
Editor: 	Sociedade Brasileira de Genética	
Relação: 	10.1590/S1415-47572010005000054	
Formato: 	text/html	
Fonte: 	Genetics and Molecular Biology  v.33 n.3 2010	
Fonte: 	info:eu-repo/semantics/openAccess