Data/hora: 12/06/2024 08:04:54

Provedor de dados: | 74
País: | Brazil
Título: | Schizophrenia is not associated with the ERBB3 gene in a Han Chinese population sample: results from case-control and family-based studies
Autores: | Li,Dawei; He,Guang; Xu,Yifeng; Duan,Yun; Gu,Niufan; Li,Xingwang; Shi,Yongyong; Qin,Wei; Feng,Guoyin; He,Lin.
Data: | 2009-01-01
Ano: | 2009
Palavras-chave: | Schizophrenia; ERBB3 gene.
Resumo: | ERBB3 (v-erb-b2 erythroblastic leukemia viral oncogene homolog 3), encoding a receptor of neuregulin-1 (NRG1), has been considered a functional candidate gene for schizophrenia susceptibility. In order to investigate a relationship between ERBB3 gene and schizophrenia in the Chinese population, case-control and family-based studies were carried out in 470 cases matched by controls, and in 532 family trios. Our results failed to show any evidence of significant association between the ERBB3 rs2292238 polymorphism and schizophrenia.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572009000400011
Editor: | Sociedade Brasileira de Genética
Relação: | 10.1590/S1415-47572009005000088
Formato: | text/html
Fonte: | Genetics and Molecular Biology  v.32 n.4 2009
Fonte: | info:eu-repo/semantics/openAccess