Data/hora: 09/06/2024 05:47:09

Provedor de dados: 	74	
País: 	Brazil	
Título: 	A model for the RecA protein of Mycoplasma synoviae	
Autores: 	Fonseca,Marbella Maria; Alarcon,Frank J.B.; Vasconcelos,Ana Tereza de; Agnez-Lima,Lucymara Fassarela.	
Data: 	2007-01-01	
Ano: 	2007	
Palavras-chave: 	DNA repair; Recombination; RecA; Mycoplasma synoviae.	
Resumo: 	In this work, we predict a structural model for the RecA protein from M. synoviae (MsRecA) by theoretical homology modeling and evaluate the occurrence of polymorphisms in this protein within several isolates of this species. The structural model suggested for MsRecA conserves the main domains present in MtRecA and EcRecA. The L1 and L2 regions showed six and three amino acid substitutions, respectively, which apparently do not affect the conformation and function of MsRecA. The C-terminal domain is shorter than that found in EcRecA and MtRecA, which may increase its capacity to bind dsDNA and displace SSB, compensating the absence of recombination initiation enzymes. The MS59 isolate RecA sequence showed one polymorphism which does not affect its functions since these belong to the same physical-chemical group.	
Tipo: 	Info:eu-repo/semantics/article	
Idioma: 	Inglês	
Identificador: 	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572007000200018	
Editor: 	Sociedade Brasileira de Genética	
Relação: 	10.1590/S1415-47572007000200018	
Formato: 	text/html	
Fonte: 	Genetics and Molecular Biology  v.30 n.1 suppl.0 2007	
Fonte: 	info:eu-repo/semantics/openAccess