Data/hora: 05/06/2024 15:58:18

Provedor de dados: | 77
País: | Chile
Título: | Effect of Prolonged Oral Administration of Aqueous Ficus sycomorus Stem-bark Extract on Testicular Size of Growing Albino Rat
Autores: | Igbokwe,N. A; Igbokwe,I. O; Sandabe,U. K.
Data: | 2010-12-01
Ano: | 2010
Palavras-chave: | Ficus sycomorus extract; Testicular size; Testicular histopathology; Spermatogenesis; Male reproductive risk.
Resumo: | Decoction of Ficus sycomorus stem bark is used to treat infertility involving low sperm counts, but the reproductive risk associated with its use is uncertain. The aqueous stem-bark extract was orally administered at 200-600 mg/kg for 30 days to post-pubertal growing albino rats. Within the period, the live body weights, scrotal diameters and testicular size parameters were estimated. The mean live body weight, scrotal diameter of the control and treated rats significantly (p&lt;0.05) increased as the animals grew, but the treatment did not significantly (p&gt;0.05) affect the parameters. There were no significant (p&gt;0.05) variations in mean testicular size parameters in treated and control rats, and no dose-dependent nor time-dependent effects occurred. Sections of the testes of the treated animals showed active spermatogenesis in the seminiferous tubules with no apparent histological lesions. It is concluded that the use of the crude extract of the Ficus sycomorus within our dose range portends minimal male reproductive risk and underscores the need to study its pro-spermatic effect.
Tipo: | Journal article
Idioma: | Inglês
Identificador: | http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022010000400052
Editor: | Sociedad Chilena de Anatomía
Formato: | text/html
Fonte: | International Journal of Morphology  v.28 n.4 2010