Data/hora: 06/06/2024 02:21:01

Provedor de dados: | 80
País: | Brazil
Título: | Decrease in hepatitis B prevalence among blood donors in Central-West Brazil
Autores: | Lindenberg,Andréa de Siqueira Campos; Motta-Castro,Ana Rita Coimbra; Puga,Marco Antonio; Ortiz Tanaka,Tayana Serpa; Torres,Marina Sawada; Fernandes-Fitts,Sonia Maria; Cunha,Rivaldo Venancio.
Data: | 2013-01-01
Ano: | 2013
Palavras-chave: | Hepatitis B virus; Prevalence; Blood donors.
Resumo: | Background The aim of the present study was to estimate hepatitis B virus seroprevalence among first-time blood donors in the city of Campo Grande, Mato Grosso do Sul State, in the central-western region of Brazil. Findings A retrospective analysis of first-time voluntary blood donor records, from January 2010 to December 2010, was conducted at the Hematology Center of Mato Grosso do Sul. The prevalence of the HBsAg and anti-HBc serological markers and their respective 95% confidence intervals were calculated. Chi-square analysis was performed between the seroprevalence previously found in 2001 and the one determined by the current study. Results were considered statistically significant if p &lt; 0.05. Among 8,840 subjects, 269 (3.04%, 95% CI: 2.7-3.4) were positive for HBV markers. The prevalence rate of HBsAg was 0.19% (95% CI: 0.1-0.3) and anti-HBc alone was 2.85% (95% CI: 2.5-3.2). Conclusions There was no statistically significant difference regarding gender. However, an important association was observed between HBV infection and older age ( p &lt; 0.01). The seroprevalence of HBV infection in first-time blood donors diminished from 2001 to 2010 ( p &lt; 0.01). Such decrease suggests an improvement in the recruitment of safe donors, the positive impact of vaccination programs and the decreasing of HBV infection prevalence in the general population.
Tipo: | Info:eu-repo/semantics/other
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992013000100402
Editor: | Centro de Estudos de Venenos e Animais Peçonhentos
Relação: | 10.1186/1678-9199-19-7
Formato: | text/html
Fonte: | Journal of Venomous Animals and Toxins including Tropical Diseases  v.19 2013
Fonte: | info:eu-repo/semantics/openAccess