Data/hora: 13/06/2024 12:17:14

Provedor de dados: | 80
País: | Brazil
Título: | Interleukin-15: its role in microbial infections
Autores: | Bannwart,C.F.; Nakaira,E.T.; Sartori,A.; Peraçoli,M.T.S.
Data: | 2007-01-01
Ano: | 2007
Palavras-chave: | Interleukin-15; Microbial infections; Innate immunity.
Resumo: | Interleukin-15 (IL-15) is a pleiotropic cytokine which regulates the proliferation, survival and the secretory activities of many distinct cell types in the body. This cytokine is produced by macrophages and many other cell types in response to infectious agents; it controls growth and differentiation of T and B lymphocytes, activation of Natural Killer (NK) and phagocytic cells, and contributes to the homeostasis of the immune system. The present review focuses on the biological and modulatory effects of IL-15 in microbial infections and shows that this cytokine may play a role in the host defense against infections by inducing activation of effector cells from both innate and adaptive immune system.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992007000300002
Editor: | Centro de Estudos de Venenos e Animais Peçonhentos
Relação: | 10.1590/S1678-91992007000300002
Formato: | text/html
Fonte: | Journal of Venomous Animals and Toxins including Tropical Diseases  v.13 n.3 2007
Fonte: | info:eu-repo/semantics/openAccess