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Provedor de dados:  Nature Precedings
País:  United Kingdom
Título:  Development of a sampling regime for research with environmental relevance based on variability of transgene expression in plants
Autores:  Carla Struzyna-Schulze
Heike Mikschofsky
Wenke Mönkemeyer
Jörg Schmidtke
Kerstin Schmidt
Inge Broer
Data:  2010-05-11
Ano:  2010
Palavras-chave:  Biotechnology
Plant Biology
Resumo:  Transgenic plants often produce proteins that are unknown in conventional crops. Therefore, it requires a fundamental analysis before approval of a new genetically modified plant is given. Since the EFSA-guidelines for risk assessment on transgenic plants provide only recommendations but no detailed instructions, we wanted to develop a valid test scheme that defines sample size and sampling organ to enable a statically valid and efficient analysis of transgene expression and its variability. The scheme will be based on data obtained for the variability in expression i. of different recombinant proteins in one variety; ii. of different integration sites of one transgene in one variety; iii. of the same recombinant protein between different varieties and between isogenic clones in a variety. The optimization of experimental procedures shall enable the development of cost and time efficient and valid sampling systems that will be used as a part of the Decision Support System (DSS) that is developed by BioOK.
Tipo:  Poster
Fonte:  Nature Precedings
Direitos:  Creative Commons Attribution 3.0 License

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