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Provedor de dados:  BJMBR
País:  Brazil
Título:  Rotavirus and reovirus interaction with mouse peritoneal resident phagocytic cells
Autores:  Guimarães,M.A.A.M.
Nozawa,C.M.
Guimarães,A.C.C.
Ramos,S.
Data:  1997-10-01
Ano:  1997
Palavras-chave:  Rotavirus
Reovirus
Phagocytic cells
Resumo:  Rotaviruses and reoviruses are involved in human and animal diseases. It is known that both viruses penetrate the gastrointestinal tract but their interaction with phagocytic cells is unknown. To study this interaction, peritoneal resident phagocytic cells were used and rotavirus and reovirus replication in peritoneal phagocytic cells was observed. However, rotavirus replication in these cells led to the production of defective particles since MA-104 cells inoculated with rotavirus phagocytic cell lysate did not show any evidence of virus replication. On the basis of these results, we suggest that, although reovirus dissemination may be helped by these phagocytic cells, these cells may control rotavirus infection and probably contribute to the prevention of its dissemination.
Tipo:  Info:eu-repo/semantics/article
Idioma:  Inglês
Identificador:  http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1997001000008
Editor:  Associação Brasileira de Divulgação Científica
Relação:  10.1590/S0100-879X1997001000008
Formato:  text/html
Fonte:  Brazilian Journal of Medical and Biological Research v.30 n.10 1997
Direitos:  info:eu-repo/semantics/openAccess
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