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A structural perspective on the mechanisms of quorum sensing activation in bacteria
Provedor de dados: 42
Autores: LIXA,CAROLINA; MUJO,AMANDA; ANOBOM,CRISTIANE D.; PINHEIRO,ANDERSON S.
Bacteria are able to synchronize the population behavior in order to regulate gene expression through a cell-to-cell communication mechanism called quorum sensing. This phenomenon involves the production, detection and the response to extracellular signaling molecules named autoinducers, which directly or indirectly regulate gene expression in a cell density-dependent manner. Quorum sensing may control a wide range of biological processes in bacteria, such as bioluminescence, virulence factor production, biofilm formation and antibiotic resistance. The autoinducers are recognized by specific receptors that can either be membrane-bound histidine kinase receptors, which work by activating cognate cytoplasmic response regulators, or cytoplasmic receptors...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Autoinducer; Bacteria; Quorum sensing; Receptor; Structure.
Ano: 2015
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652015000502189