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Effect of Preconception Gamma Irradiation on Morphometric Assessment of Adult Female Mice and Embryo
Provedor de dados: 77
Autores: Edagha,Innocent A; Shokunbi,Matthew T; Adenipekun,Adeniyi A; Bassey,Rosemary B; Ekong,Moses B.
The aim was to study the effect of preconception gamma irradiation on the gross morphometry of the adult female mice and its embryo. Twenty-seven mice; 18 females and 9 males: subdivided into 3 groups namely (Control, Non-Irradiation and Radiation) containing 6 females and 3 male mice each in 2:1 ratio. A gamma irradiation dose of 1Gy/min was delivered to each batch of mice exposed by a Cobalt 60, Theratron 780c model, by Atomic Energy of Canada Limited (AECL) at the Radiotherapy department of the University College Hospital, Ibadan. All the animals were mated 1 week post irradiation. Vaginal plugs were confirmed, and the pregnant females were sacrificed on day 14 of gestation by chloroform inhalation. The gross morphology of the female mice and their...
Tipo: Journal article
Palavras-chave: Preconception; Irradiation; Gamma ray; Spinal cord; Embryo.
Ano: 2013
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022013000200039