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Data/hora: 07/06/2024 02:17:11

Cycle modulation of insulin-like growth factor-binding protein 1 in human endometrium
Provedor de dados: 56
Autores: Corleta,H.; Capp,E.; Strowitzki,T.
Endometrium is one of the fastest growing human tissues. Sex hormones, estrogen and progesterone, in interaction with several growth factors, control its growth and differentiation. Insulin-like growth factor 1 (IGF-1) interacts with cell surface receptors and also with specific soluble binding proteins. IGF-binding proteins (IGF-BP) have been shown to modulate IGF-1 action. Of six known isoforms, IGF-BP-1 has been characterized as a marker produced by endometrial stromal cells in the late secretory phase and in the decidua. In the current study, IGF-1-BP concentration and affinity in the proliferative and secretory phase of the menstrual cycle were measured. Endometrial samples were from patients of reproductive age with regular menstrual cycles and...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: IGF-1; Binding protein; Endometrium.
Ano: 2000
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2000001100019