Consulta: creatorFacets:"Deslandes, Eric"
Registros recuperados: 2
Data/hora: 08/06/2024 15:24:11

Floridoside extracted from the red alga Mastocarpus stellatus is a potent activator of the classical complement pathway
Provedor de dados: 5
Autores: Courtois, Anthony; Simon-colin, Christelle; Boisset, Claire; Berthou, Christian; Deslandes, Eric; Guezennec, Jean; Bordron, Anne.
Many biological properties of algae have been found to have useful applications in human health, particularly in the fields of oncology and immunology. Floridoside, extracted from the red alga Mastocarpus stellatus, has a structure similar to the xenoantigen Gal alpha 1-3 Gal. This xenoantigen has been described to induce a high immune response in human xenografts and is mediated by natural anti-gal antibodies that activate the classical complement pathway. Based on this property, we analyzed the potential activities of floridoside on the immune system. We demonstrated that floridoside activates a complement cascade via the classical complement pathway, through the recruitment and activation of natural IgM. This algal molecule could represent an important...
Tipo: Text
Palavras-chave: Complement system; Immunomodulation; Marine algae; Alpha galactosyl glycerol.
Ano: 2008
URL: http://archimer.ifremer.fr/doc/2008/publication-6248.pdf

Isolation and partial characterization of bacteria (Pseudoalteromonas sp.) with potential antibacterial activity from a marine costal environment from New Caledonia
Provedor de dados: 5
Autores: Dufourcq, R.; Chalkiadakis, Eletherios; Fauchon, M.; Deslandes, Eric; Kerjean, V.; Chanteau, S.; Petit, Elodie; Guezennec, Jean; Dupont-rouzeyrol, M.
Marine bacteria are a rich source of bioactive metabolites. However, the microbial diversity of marine ecosystem still needs to be explored. The aim of this study was to isolate and characterize bacteria with antimicrobial activities from various marine coastal environment of New Caledonia. We obtained 493 marine isolates from various environments and samples of which 63 (12.8%) presented an antibacterial activity against a panel of reference pathogenic strains (Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli and Enterococcus faecalis). Ten out of the most promising strains were cultured, fractionated and screened for antibacterial activity. Four of them (NC282, NC412, NC272 and NC120) showed at least an activity against reference and...
Tipo: Text
Palavras-chave: Antibacterial activity; Characterization; Marine bacteria; New Caledonia; Screening.
Ano: 2014
URL: http://archimer.ifremer.fr/doc/00174/28552/26994.pdf