Consulta: creatorFacets:"Figueiredo,José Fernando de Castro"
Registros recuperados: 4
Data/hora: 14/06/2024 03:18:28

HCV virological response during treatment of chronic hepatitis C is associated with liver histological Improvement in patients with HCV/HIV co-infection
Provedor de dados: 55
Autores: Castro,Gleusa; Ramalho,Leandra Naira Zambelli; Zucoloto,Sérgio; Martinelli,Ana de Lourdes Candolo; Figueiredo,José Fernando de Castro.
Liver histological improvement after treatment for chronic hepatitis C in patients co-infected with human immunodeficiency virus-1 (HIV-1) has been described. Paired liver biopsies in twenty six HCV/HIV co-infected patients were compared to determine factors possibly associated with histological improvement. The patients were submitted to a liver biopsy before treatment for hepatitis C and 25 months after the end of treatment. Fragments of the liver biopsy obtained before and after treatment were compared regarding the following parameters: histological activity index (HAI) and degree of fibrosis (Knodell); intensity of collagen deposits (Sirius Red staining) and degree of stellate cell activation (alpha-smooth muscle actin labeling). The ratios of the...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Chronic hepatitis C; Hepatic stellate cell; Histological response; Human immunodeficiency virus; Paired liver biopsies.
Ano: 2008
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702008000300004

Long-term follow-up of patients with chronic hepatitis C with sustained virologic response to interferon
Provedor de dados: 55
Autores: Ferreira,Sandro da Costa; Carneiro,Marcos de Vasconcelos; Souza,Fernanda Fernandes; Teixeira,Andreza Corrêa; Villanova,Marcia Guimarães; Figueiredo,José Fernando de Castro; Passos,Afonso Dinis Costa; Ramalho,Leandra Naira Zambelli; Zucoloto,Sergio; Martinelli,Ana de Lourdes Candolo.
BACKGROUND AND AIM: The durability of the sustained virologic response (SVR) in patients with chronic hepatitis C after treatment and the ideal follow-up time for these patients remains undefined. The objective of the study was to evaluate the durability of the virologic response in patients with chronic hepatitis C followed up for at least 12 months after SVR at HCFMRP-USP. METHODS: The study was conducted on 174 patients with chronic hepatitis C treated with different antiviral regimens who had achieved SVR. Qualitative serum HCV-RNA was determined by the commercial kit (COBAS AMPLICOR HCV, v2.0). RESULTS: There was predominance of male (73%) with a mean age of 45.6 ± 10 years. Liver cirrhosis was present in 16.1% of the study subjects. Mean follow-up...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Hepatitis C; Interferon; HCV; Follow-up; Hepatocellular carcinoma.
Ano: 2010
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702010000400003

HLA profile in patients with AIDS and tuberculosis
Provedor de dados: 55
Autores: Figueiredo,José Fernando de Castro; Rodrigues,Maria de Lourdes Veronese; Deghaide,Neifi Hassam Saloum; Donadi,Eduardo Antonio.
Studies carried out in various populations have reported an association between some HLA specificities and susceptibility to tuberculosis. We investigated the class I and class II HLA profile in Brazilian patients of various ethnic backgrounds who had AIDS and tuberculosis. Twenty-two adult patients with AIDS and tuberculosis (Group I), 103 patients with AIDS without tuberculosis (Group II) and 423 healthy individuals not infected with HIV (Group III) were evaluated. Diagnosis of HIV infection was made by ELISA, confirmed by a gelatin particle agglutination test. Diagnosis of tuberculosis was made based on clinical/radiological presentation and direct bacilloscopy or clinical specimen cultures. Class I antigens were typed by microlymphotoxicity. Class II...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: AIDS; Tuberculosis; Host genetic factors; HLA.
Ano: 2008
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702008000400004

Ocular problems in brazilian patients with AIDS before and in highly active antiretroviral therapy (HAART) era
Provedor de dados: 55
Autores: Rodrigues,Marcia Lopes; Rodrigues,Maria de Lourdes Veronese; Figueiredo,José Fernando de Castro; Freitas,João Alberto Holanda de.
This study determined the total frequency of patients with AIDS and ophthalmologic problems before and after the introduction of combined highly active antiretroviral therapy (HAART), regardless of the use of this treatment; it also determined the frequency of external ocular diseases, intraocular infections and inflammations, and problems of the anterior portion of the optic nerve in these two groups of patients; and it determined the differences in the frequency of ophthalmologic problems in patients receiving HAART or not. This was a retrospective study of 207 patients examined using the same protocol, from June 1995 to February 1998 (n=58, pre-HAART era) and from March 1998 to May 2005 (n=149, HAART era). The frequency of ophthalmologic problems was...
Tipo: Info:eu-repo/semantics/article
Palavras-chave: Ocular problems; AIDS; HAART.
Ano: 2007
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702007000200005